About 5 — Sports Performance Lab, Texas Tech University

Research Publications

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Luk HY, Appell CR, Jiwan NC, Vellers HL, Sekiguchi Y, Levitt DE. Fluid Restriction Enhances Mitochondrial Stress in Peripheral Blood Mononuclear Cells Following High-Volume Resistance Exercise in Health Young Males (2026). American Journal of Physiology-Cell Physiology. 1;330(6):1631-1646.
Keefe MS, Dunn, RA, Appell CR, Jiwan NC, Luk HY, Rolloque JJS, Sekiguchi Y, The Effect of Muscle-Damaging Exercise in the Heat on Sleep (2026). Sports Health. [epub ahead of print].
Sekiguchi Y, Ky AT, Benjamin CL, Rolloque JJS, Griswold JA, Kavouras SA, Adams JD. Oral Rehydration Improved Exercise Performance and Decreased Core Temperature and Heart Rate Compared to Intravenous Rehydration in Recreational Active m Males (2026). Sports Health. [epub ahead of print]
Hernandez MI, Jiwan NC, Appell CR, Dunn RA, Ky AT, Keefe MS, Luk HY, Sekiguchi Y. Dehydration Reduces Heart Rate Variability in Recreationally Resistance-Trained Men (2026). The Journal of Sports Medicine and Physical Fitness. [epub ahead of print]
Bowie JS, Szymanski MR, Struder JF, Filep EM, Morrissey-Basler MC, Brewer GJ, Thornton SN, Mahoney KJ, Sekiguchi Y, Kwon OS, Ki H. Chon KH, Casa DJ, Lee EC. Heat Tolerance Classification Criteria Require Population-Specific Thresholds for Accurate Assessment of Acclimation State (2026). Physiological Reports. 14(4):1-15.
Elliott KB, Keefe MS, Dunn RA, Palmer TB, Lepley AS. Sekiguchi Y. Hypohydration Decreases Neuromuscular Performance Prior to and Following Intermittent Exercise in the Heat (2026). Medicine & Science in Sports & Exercise. 58(6):1259-1274.
Wardenaar FC, Burns SF, Campos M, Chan Y , Claassen-Smithers A, Dunshea-Mooij C, Haddou SE , Hoogervorst D, Jagim A, Reinaldo P, Garcia, Garthe I, Nugent AP, Aly MO, Saunders B, Schott KD, Sekiguchi Y, Slater G, Speers N, Aussieker T. Navigating the Risks Beyond the Label: Unpacking Global Nutritional Supplement Safety (2025). International Journal of Sport Nutrition & Exercise Metabolism [epub ahead of print].
Keefe MS, Levitt DE, Vellers HL, Benjamin CL, Sekiguchi Y. Mitochondrial Adaptations from Heat Acclimation – A Narrative Review. Journal (2025). Journal of Thermal Biology. 133: 104283: 1-11.
Wardenaar FC, Aussieker T, Dolan E, Campos CF, Kavouras SA, Ormsbee M, Rawson E, Saunders B, Schott K, Sekiguchi Y, Burke LM. Summary of the 2025 PINES "10 questions / 10 experts” session – Can normal foods replace some ergogenic supplements and commercially available sports foods? (2025) International Journal of Sport Nutrition & Exercise Metabolism. 36(1): 52-61.
Sekiguchi Y, Jiwan NC, Appell CR, Moya RM, Ky AT, Keefe MS, Dunn RA, Luk HY. Impact of Hydration Status on Sleep and Recovery After Heavy Resistance Exercise (2025). Journal of Strength and Conditioning Research. 39 (12): 1278-1283.
Luk HY, Jiwan NC, Appell CR, Vellers HL, Levitt DE, Sekiguchi Y. Passive Dehydration Increases Oxidative Stress and mTOR Signaling Pathway Activation in Young Men Following Resistance Exercise (2025). The Journal of Physiology. 603 (12):3351-3570.
Ky AT, Dunn RA, Keefe MS, Sekiguchi Y. Thirst Modulates Parasympathetic Recovery: Comparing Oral and Intravenous Rehydration (2025). Physiologia. 5(16): 1-9.
Sekiguchi Y, Adams WM, Hosokawa Y, Benjamin CL, Stearns RL, Huggins RA, Casa DJ. Customizing Individual Heat Mitigation Strategies to Optimize Performance in Elite Athletes (2025). Frontiers in Physiology. 16:1-16.
Ky AT, Giersch GEW, Sekiguchi Y*, Dunn L, Casa DJ, Armstrong LE, Lee EC. Mild Dehydration by 24h Fluid Restriction Led to Difficulty Falling Sleeping and Increased Sleep Duration (2025). SN Comprehensive Clinical Medicine. 7(16): 1-7.
Armstrong LE, Stearns RL, Huggins RA, Sekiguchi Y, Mershon AJ, Casa DJ. Reference Values for Hydration Biomarkers: Optimizing Athletic Performance and Recovery (2025). Open Access Journal of Sports Medicine.16:31-50.
Keefe MS, Luk HY, JRolloque JJS, Jiwan NC, Sekiguchi Y. Hydration Assessment in Males and Females using the WUT (Weight, Urine Color, and Thirst) Venn Diagram compared to Blood and Urinary Indices (2025). Nutrient. 14; 17 (4), 689:1-10.
Appell CR, Jiwan NC, Sekiguchi Y,Luk HY. Passive Dehydration Reduces Muscle Thickness After Resistance Exercise (2025). Journal of Sports Sciences. 43 (4), 336: 336-347.
Dunn RA, Tinsley GM, Palmer TB, Benjamin CL, Sekiguchi Y. The Efficacy of Nutritional Strategies and Ergogenic Aids on Acute Responses and Chronic Adaptations to Exertional-Heat Exposure: A Narrative Review (2024). Nutrient.5;16 (22), 3792:1-25.
Keefe MS, Benjamin CL, Casa DJ, Sekiguchi Y. Importance of Electrolytes on Exercise Performance and Assessment Methodology after Heat Training: A Narrative Review (2024). Applied Sciences. 14 (22), 10103: 1-12.
Elliott KB, Keefe MS, Rolloque JJS, Jiwan NC, Dunn RA, Luk HY, Sekiguchi Y. Relationships between Morning Thirst and Later Hydration Status and Total Water Intake (2024). Nutrient. 16 (18), 3212: 1-10.
Dunn RA, Luk HY, Appell CR, Jiwan NC, Keefe MS, Rolloque JJS, Sekiguchi Y. Eccentric muscle-damaging exercise in the heat lowers cellular stress prior to and immediately following future exertional-heat exposure (2024). Cell Stress and Chaperones. 29 (3):472-482.
Dunn RA, Fry LA, Sekiguchi Y*, Benjamin CL, Manning CN, Higgins RA, Stearns RL, Casa DJ. The Effects of Heat Acclimatization, Heat Acclimation, and Intermittent Heat Training on Maximal Oxygen Update (2024). Sports Health. 27(2): 305-311.
Keefe MS, Luk HY, Rolloque JJS, Sekiguchi Y. The WUT (Weight, Urine Color, and Thirst) Venn Diagram Accurately Assesses Hydration Status in Males and Females (2024). British Journal of Nutrition. 14; 131(7): 1181-1188.
Sekiguchi Y, Hosokawa Y, Dadzie E, Lopez III V, Bivona JJ, Thornton SN, Jardine JF, Casa DJ, Elaine C. Lee EC. Change in Interleukin (IL)-6, 8, and 10 and its Association with an Increase in Core Temperature following a 7-mile Running Race in the Warm Weather (2024). Research in Sports Medicine. 33 (1): 107-116.